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51.Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent
Yingfeng Yang, Hanze Ying, Zhixia Li, Jiang Wang, Yingying Chen, Binbin Luo, Danielle L. Gray, Andrew Ferguson, Qian Chen, Y. Z and Jianjun Cheng*
Nature Communications, 12, 1572 (2021) [LINK] [PDF]
50.Nanoscale Cinematography of Soft Matter System under Liquid-Phase TEM
Zihao Ou, Chang Liu, Lehan Yao, and Qian Chen*
Accounts of Materials Research, 1 (1), pp 41–52 (2020) [LINK] [PDF]
49.Mechanistic insight into gold nanorod transformation in nanoscale confinement of ZIF-8
Cheongwon Bae, Jaedeok Lee, Lehan Yao, Suhyeon Park, Yeonju Lee, Jieun Lee, Qian Chen and Juyeong Kim*
Nano Research, 14, pp 66–73 (2020) [LINK] [PDF]
48.Imaging how thermal capillary waves and anisotropic interfacial stiffness shape nanoparticle supracrystals
Zihao Ou, Lehan Yao, Hyosung An, Bonan Shen and Qian Chen*
Nature Communications, 11, 4555 (2020) [LINK] [PDF]
- Selected to Nature Communications editors' Highlight in materials science and chemistry. Click here for details.
47.Nucleation, growth, and superlattice formation of nanocrystals observed in liquid cell transmission electron microscopy
Qian Chen, Jong Min Yuk, Matthew R. Hauwiller, Jungjae Park, Kyun Seong Dae, Jae Sung Kim and A. Paul Alivisatos
MRS Bulletin, 45 (9), pp 713-726 (2020) [LINK] [PDF]
46.Liquid-phase Electron Microscopy Imaging of Cellular and Biomolecular Systems
John W. Smith and Qian Chen*
Journal of Materials Chemistry B, 8, pp 8490-8506 (2020) [LINK] [PDF]
45. Machine Learning to Reveal Nanoparticle Dynamics from Liquid-Phase TEM Videos
Lehan Yao, Zihao Ou, Binbin Luo, Cong Xu, and Qian Chen*
ACS Central Science, 6 (8), pp 1421-1430 (2020) [LINK] [PDF]
- Selected as front cover of the issue. Click here for details.
- Highlighted @ ILLINOIS NEWS BUREAU: ''Machine learning peeks into nano-aquariums''
Other news reports: Nanowerk, EurekAlert!,
44. Interfacial crystallization under DNA control
Chang Liu, and Qian Chen*
Nature Materials, 19, pp 704–705 (2020) [LINK] [PDF]
43.“Colloid–Atom Duality” in the Assembly Dynamics of Concave Gold Nanoarrows
Chang Liu, Zihao Ou, Fucheng Guo, Binbin Luo, Wenxiang Chen, Limin Qi, and Qian Chen*
Journal of the American Chemical Society, 142 (27), pp 11669-11673 (2020)[LINK] [PDF]
42.Monolithic mtesla-level magnetic induction by self-rolled-up membrane technology
Wen Huang, Zhendong Yang, Mark D. Kraman, Qingyi Wang, Zihao Ou, Miguel Muñoz Rojo, Ananth Saran Yalamarthy, Victoria Chen, Feifei Lian, Jimmy H. Ni, Siyu Liu, Haotian Yu, Lei Sang, Julian Michaels, Dane J. Sievers, J. Gary Eden, Paul V. Braun, Qian Chen, Songbin Gong, Debbie G. Senesky, Eric Pop and Xiuling Li*
Science Advances, 6 (3), eaay4508 (2020) [LINK] [PDF]
41.Kinetic pathways of crystallization at the nanoscale
Zihao Ou¶, Ziwei Wang¶, Binbin Luo, Erik Luijten*, and Qian Chen*
Nature Materials, 19, pp 450–455 (2020) [LINK] [PDF]
- Watch the video
- Selected as News & Views @ Nature Materials : ''Seeing crystal formation one particle at a time"
- Highlighted @ ILLINOIS NEWS BUREAU: ''Crystallization clarified, researchers report"
- Highlighted @ MRS Bulletin: ''Crystallization pathway imaged in real time at the nanoscale"
40.Charting the quantitative relationship between two-dimensional morphology parameters of polyamide membranes and synthesis conditions
Hyosung An, John W. Smith, Wenxiang Chen, Zihao Ou and Qian Chen*
Molecular Systems Design & Engineering, 5, pp 102-109 (2020) [LINK] [PDF]
- Selected as front cover of the issue. Click here for details.
- Selected by editors as a HOT MSDE article. Click here for details.
39.Multivalent Polymer–Peptide Conjugates: A General Platform for Inhibiting Amyloid Beta Peptide Aggregation
Xing Jiang, Abigail J. Halmes, Giuseppe Licari, John W. Smith, Yang Song, Edwin G. Moore, Qian Chen*, Emad Tajkhorshid*, Chad M. Rienstra*, Jeffrey S. Moore*
ACS Macro Letters, 8, pp 1365-1371 (2019) [LINK] [PDF]
38.Polymer−Peptide Conjugates Convert Amyloid into Protein Nanobundles through Fragmentation and Lateral Association
John W. Smith, Xing Jiang, Hyosung An, Alexander M. Barclay, Giuseppe Licari, Emad Tajkhorshid, Edwin G. Moore, Chad M. Rienstra*, Jeffrey S. Moore*, and Qian Chen*
ACS Applied Nano Materials, 3(2), pp 937-945 (2020) [LINK] [PDF]
37.Tip-Patched Nanoprisms from Formation of Ligand Islands
Ahyoung Kim, Shan Zhou, Lehan Yao, Stacey Ni, Binbin Luo, Charles E Sing, and Qian Chen*
Journal of the American Chemical Society, 141 (30), pp 11796-11800 (2019)[LINK] [PDF]
36.Real-time Electron Microscopy of Protein Nanodiscs in Graphene Liquid Cells
John W. Smith, Lauren N. Carnevale, Aditi Das and Qian Chen*
Microscopy and Microanalysis, 25 (S2), pp 1498-1499 (2019) [LINK] [PDF]
35.Determination of Crystallinity in Li1−xMgxMn2O4 Nanocrystals Based on Diffraction Patterns Correlation Analysis and Strain Mapping
Xun Zhan, Renliang Yuan , Wenxiang Chen, Qian Chen* and Jian-Min Zuo
Microscopy and Microanalysis, 25 (S2), pp 1972-1973 (2019) [LINK] [PDF]
34.Liquid-phase TEM imaging of self-assembly pathways of anisotropic nanoparticles
Zihao Ou, Binbin Luo, Chang Liu, and Qian Chen*
Microscopy and Microanalysis, 25 (S2), pp 1414-1415 (2019) [LINK] [PDF]
33.Effects of Particle Size on Mg2+ Ion Intercalation into λ-MnO2 Cathode Materials
Wenxiang Chen, Xun Zhan, Binbin Luo, Zihao Ou, Pei-Chieh Shih, Lehan Yao, Saran Pidaparthy, Arghya Patra, Hyosung An, Paul V. Braun, Ryan M. Stephens, Hong Yang, Jian-Min Zuo* and Qian Chen*
Nano Letters, 19, pp 4712-4720 (2019). [LINK] [PDF]
32.Hierarchical self-assembly of 3D lattices from polydisperse anisometric colloids
Binbin Luo, Ahyoung Kim, John W. Smith, Zihao Ou, Zixuan Wu, Juyeong Kim and Qian Chen*
Nature Communications, 10, 1815 (2019) [LINK] [PDF]
- Highlighted ''Multistep self-assembly opens door to new reconfigurable materials'' Read the full news article here @ ILLINOIS NEWS BUREAU.
Other news reports:, NSF science news, and nanotech-now.
- Selected to Nature Communications editors' Highlight in Inorganic, Nanoscale and Physical Chemistry. Click here for details.
31.Unraveling the Morphology–Function Relationships of Polyamide Membranes Using Quantitative Electron Tomography
Xiaohui Song, John W. Smith, Juyeong Kim, Nestor J. Zaluzec, Wenxiang Chen, Hyosung An, Jordan M. Dennison, David G. Cahill, Matthew A. Kulzick, and Qian Chen*
ACS Applied Materials & Interfaces 11 (8), pp 8517–8526 (2019). [LINK] [PDF]
30.Reconfigurable nanoscale soft materials
Zihao Ou, Ahyoung Kim, Wen Huang, Paul V. Braun, Xiuling Li, and Qian Chen*
Current Opinion in Solid State and Materials Science 23 (1), pp 41-49 (2019). [LINK] [PDF]
29.Soft Matter X-ray Microanalysis in the Analytical Electron Microscope
Mikhail Ovsyanko, Emrah Yucelen, Evgeniya Pechnikova, Meiken Falke, Qian Chen* and Nestor J. Zaluzec
Microscopy and Microanalysis, 24 (S1), pp 776-777 (2019) [LINK] [PDF]
28.Colloidal Metal-Organic Framework Hexapods Prepared from Post-Synthesis Etching with Enhanced Catalytic Activity and Rollable Packing
Zihao Ou, Xiaohui Song, Wen Huang, Xing Jiang, Subing Qu, Qingyi Wang, Paul V. Braun, Jeffrey S. Moore, Xiuling Li, and Qian Chen*
ACS Applied Materials & Interfaces 10 (48), pp 40990–40995 (2018). [LINK] [PDF]
27.Reconfigurable polymer shells on shape-anisotropic gold nanoparticle cores
Juyeong Kim, Xiaohui Song, Ahyoung Kim, Binbin Luo, John W. Smith, Zihao Ou, Zixuan Wu and Qian Chen*
Macromolecular Rapid Communications 39, 1800101 (2018). [LINK] [PDF]
26.Size control of cross-linked carboxy-functionalized polystyrene particles: Four orders of magnitude of dimensional versatility
Nina M. Sekerak, Kristin M. Hutchins, Binbin Luo, Jin Gu Kang, Paul V. Braun, Qian Chen and Jeffrey S. Moore
European Polymer Journal, 101, pp 202-210 (2018). [LINK] [PDF]
25.Imaging the polymerization of multivalent nanoparticles in solution
Juyeong Kim, Zihao Ou, Matthew R. Jones, Xiaohui Song and Qian Chen*
Nature Communications, 8, 761 (2017). [LINK] [PDF]
- Highlighted "Tiny aquariums put nanoparticle self-assembly on display".
Read the full news article here @ ILLINOIS NEWS BUREAU.
Other news reports: Nanowerk, EurekAlert!,, Long Room, Controlled Environments, Science Newsline, Azonano,
24.Polymerization-like co-assembly of silver nanoplates and patchy spheres
Binbin Luo, John W. Smith, Zixuan Wu, Juyeong Kim, Zihao Ou and Qian Chen*
ACS Nano 11 (8), pp 7626–7633 (2017). [LINK] [PDF]
23.Polymorphic assembly from beveled gold triangular nanoprisms
Juyeong Kim,* Xiaohui Song,* Fei Ji, Binbin Luo, Nicole F. Ice, Qipeng Liu, Qiao Zhang and Qian Chen*
Nano Letters 17 (5), pp 3270–3275 (2017). [LINK] [PDF]
- Highlighted "Playing with Nanoparticle Legos: Polymorphism in Nanoantenna Arrays".
Read the full news article here.
22.Quantifying the self-assembly behavior of anisotropic nanoparticles using liquid-phase transmission electron microscopy
Binbin Luo,* John W. Smith,* Zihao Ou and Qian Chen*
Accounts of Chemical Research 50 (5), pp 1125–1133 (2017). [LINK] [PDF]
- Selected to highlight by @ACSPublications. Click here for details.
21.Effects of cross-linking density on interfacial polymerization and scaffold Formation in functionalized polymer beads
Kristin M. Hutchins, Chih-Yi Lee, Binbin Luo, Qian Chen and Jeffrey S. Moore
Industrial & Engineering Chemical Research 56 (16), pp 4883–4886 (2017). [LINK] [PDF]
20.Single-particle mapping of nonequilibrium nanocrystal transformations
Xingchen Ye, Matthew R. Jones, Layne B. Frechette, Qian Chen, Alexander S. Powers, Peter Ercius, Gabriel Dunn, Grant M. Rotskoff, Son C. Nguyen, Vivekananda P. Adiga, Alex Zettl, Eran Rabani, Phillip L. Geissler, and A. Paul Alivisatos
Science 354, pp 874-877 (2016). [LINK] [PDF]
19.In Situ Electron Microscopy Imaging and Quantitative Structural Modulation of Nanoparticle Superlattices
Juyeong Kim, Matthew R. Jones, Zihao Ou, Qian Chen*
ACS Nano 10 (11), pp 9801–9808 (2016). [LINK] [PDF]
- Selected to highlight and interview by ACSNano Podcast.
Listen to us about this work (Episode 112 here).
18.Reversible and Precise Self-Assembly of Janus Metal-Organosilica Nanoparticles through a Linker-Free Approach
Huicheng Hu, Fei Ji, Yong Xu, Jiaqi Yu, Qipeng Liu, Lei Chen, Qian Chen, Peng Wen, Yeshayahu Lifshitz, Yan Wang, Qiao Zhang and Shuit-Tong Lee
ACS Nano 10 (8), pp 7323–7330 (2016). [LINK] [PDF]

Prior to UIUC

  1. Jungwon Park, Hans Elmlund, Peter Ercius, Jong Min Yuk, David T. Limmer, Qian Chen, Kwanpyo Kim, Sang Hoon Han, David A. Weitz, Alex Zettl, and A. Paul Alivisatos, “3D structure of individual nanocrystals in solution by electron microscopy,” Science 349, 290-295 (2015). [LINK] [PDF]
  1. Yingjie Zhang, Qian Chen, A. Paul Alivisatos, Miquel Salmeron, “Charge carrier trapping dynamics in quantum dot field effect transistors,” Nano Letters 15, 4657-4663 (2015). [LINK] [PDF]
  1. Somin E. Lee, Qian Chen, Ramray Bhat, Shayne Petkiewicz, Jessica M. Smith, Vivian E Ferry, A. Paul Alivisatos, Mina J. Bissell, “Reversible aptamer-Au plasmon rulers for secreted single molecules,” Nano Letters 15, 4564-4570 (2015). [LINK] [PDF]
  1. Qian Chen*, Hoduk Cho*, Karthish Manthiram, Mark Yoshida, Xingchen Ye, A. Paul Alivisatos, “Interaction potentials of anisotropic nanocrystals from the trajectory sampling of particle motion using in situ liquid phase transmission electron microscopy,” ACS Central Science1, 33-39 (2015). [LINK] [PDFHighlights by Kyle J. M. Bishop, “Nanoscale self-assembly: seeing is understanding”, ACS Central Science 1, 16-17 (2015). [LINK] [PDF]
  1. Kundan Chaudhary, Jaime J. Juárez, Qian Chen, Steve Granick, Jennifer A. Lewis, “Reconfigurable assemblies of Janus rods in AC electric fields,” Soft Matter 10, 1320-1324 (2014). [LINK] [PDF]
  2. Qian Chen, Jessica M. Smith, Jungwon Park, Kwanpyo Kim, Davy Ho, Haider I. Rasool, Alex Zettl, A. Paul Alivisatos, “3D motion of DNA-Au nanoconjugates in graphene liquid cell EM,” Nano Letters 13, 4556-4561 (2013). [LINK] [PDF]
  3. Xiaoming Mao, Qian Chen, Steve Granick, “Entropy favours open colloidal lattices,” Nature Materials 12, 217-222 (2013). [LINK] [PDFNews & views by Michael E. Cates, “Patchy colloids: entropy stabilizes open crystals,” Nature Materials 12, 179-180 (2013). [LINK] [PDF]
  4. Qian Chen, Jing Yan, Jie Zhang, Sung Chul Bae, Steve Granick, “Janus and multiblock colloidal particles,” Invited feature article for Langmuir 28, 13555-13561 (2012). [LINK] [PDF]
  5. Kundan Chaudhary, Qian Chen, Jaime J. Juárez, Steve Granick, Jennifer A. Lewis, “Janus colloidal matchsticks,” Journal of the American Chemical Society 134, 12901-12903 (2012). [LINK] [PDF]
  6. Qian Chen, Sung Chul Bae, Steve Granick, “Staged self-assembly of colloidal metastructures,” Journal of the American Chemical Society 134, 11080-11083 (2012). [LINK] [PDF]
  7. Qian Chen, Erich Diesel, Jonathan K. Whitmer, Sung Chul Bae, Erik Luijten, Steve Granick, “Triblock colloids for directed self-assembly,” Journal of the American Chemical Society 133, 7725-7727 (2011). [LINK] [PDF]
  8. Qian Chen, Sung Chul Bae, Steve Granick, “Directed self-assembly of a colloidal kagome lattice,” Nature 469, 381-384 (2011). [LINK] [PDFNews & views by Flavio Romano and Francesco Sciortino, “Colloidal self-assembly: patchy from the bottom up,” Nature Materials 10, 171-173 (2011). [LINK] [PDF]
  9. Qian Chen, Jonathan Whitmer, Shan Jiang, Sung Chul Bae, Erik Luijten, Steve Granick, “Supracolloidal reaction kinetics of Janus spheres,” Science 331, 199-202 (2011). [LINK][PDF]
  10. Shan Jiang, Qian Chen, Mukta Tripathy, Erik Luijten, Kenneth S. Schweizer, Steve Granick, “Janus particle synthesis and assembly,” Advanced Materials 22, 1060-1071 (2010). [LINK] [PDF]
  11. Steve Granick, Shan Jiang, Qian Chen, “Janus particles,” Physics Today 62, 68-69 (2009). [LINK] [PDF]
  12. Shan Jiang, Mitchell J. Schultz, Qian Chen, Jeffrey S. Moore, Steve Granick, “Solvent-free synthesis of Janus colloidal particles,” Langmuir 24, 10073-10077 (2008). [LINK] [PDF]
  13. Nana Zhao, Yang Wei, Nijuan Sun, Qian Chen, Jingwei Bai, Longping Zhou, Yao Qin, Meixian Li and Limin Qi, “Controlled synthesis of gold nanobelts and nanocombs in aqueous mixed surfactant solutions,” Langmuir 24, 991-998 (2008). Most-cited Langmuir articles published in 2008. [LINK] [PDF]